Repair of sheep articular cartilage defects with a rabbit costal perichondrial graft

Tissue Engineering of Articular Cartilage: Perichondrial Cells in Osteochondral Repair

Efforts to expand treatment options for articular cartilage repair have increasingly focused on the implantation of cell polymer constructs. Primary cells cultured from perichondrium, a chondrogenic tissue, were found to survive in vitro within a biodegradable porous polylactic acid matrix. These perichondrocyte-polylactic acid composite grafts were then implanted within osteochondral defects d...

Rabbit articular cartilage defects treated with cultured costal chondrocytes (preliminary report).

An attempt to repair articular cartilage defects by costal chondrocytes transplantation was made. A full-thickness defect in the rabbit's femoral patellar groove was artificially made. Cultured costal cartilage chondrocytes were then transplanted into the defects and covered with periosteal flaps. Empty defects were used as the control group. Animals were divided into two groups (five rabbits e...

Proteinpolysaccharides from human articular and costal cartilage.

Comparison of cartilage self repairs and repairs with costal and articular chondrocyte transplantation in treatment of cartilage defects in rats.

In our experiment, we tried to assess the potential of repair of full-thickness defects in articular cartilages of rabbit femurs. An artificially made, full-thickness defect in the rabbit's femoral patellar groove was created. The defects were divided into six groups. The reparative tissue was evaluated by macroscopic, histological, and immunohistochemical examinations. The reparative tissues i...

The rabbit costal cartilage reconstructive surgical model.

Rib grafts in facial plastic surgery are becoming more frequently used. Small animal models, although not ideal may be used to emulate costal cartilage-based procedures. A surgical characterization of this tissue will assist future research in the selection of appropriate costal segments, based on quantitative and qualitative properties. The objective of this study is to assess the surgical ana...